Dreamhost has a section on their Wiki explaining detailed ways on how to optimize WordPress using such tools as WP Super Cache, Nocache, Fcgi, and various combinations of the latter. I don’t understand the gobbily gook presented within the document but if you’re using your own dedicated server or VPS, these tips might be of interest to you. An aside but also interesting article regarding WordPress configuration tricks was published by Jeff Star on the Digging Into WordPress site back in 2009. Lesson learned is that the WPConfig file that is apart of WordPress is pretty powerful.
WordPress Optimization Guide By Dreamhost