In reply to OriginalEXE.

@Original,

All you have said is that someone needs to write a JS implementation of WP APIs. Maybe this is not something you and me can do by ourself but wordpress.com people sure can do.

There is a relatively big performance hit for intra server communication, therefor you want to minimize it as much as possible. No point in having node.js -> WP -> MySQL if you can just do node.js -> MySQL. You don't care about such performance stuff only if you have extra money to pay for more hardware.